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Peptide · Research use only

TB 500

$100CAD

A short peptide fragment related to thymosin beta 4 and explored in early tissue-repair research.

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TB 500$100

Product information

TB 500, clearly explained.

A short peptide fragment related to thymosin beta 4 and explored in early tissue-repair research.

Overview

TB-500 usually refers to a small fragment of the much larger thymosin beta 4 peptide. Studies of the full peptide—especially topical eye studies—cannot be treated as proof for this fragment or another delivery method.

TB-500 commonly refers to the LKKTETQ fragment associated with thymosin beta 4. Full-length thymosin beta 4 is a 43-amino-acid peptide; the fragment and parent peptide must not be treated as the same molecular entity.
Format
Vial
Available strengths
10mg
Batch
TB5 004-016
Purity
99.3%
Research at a glanceFragment-specific human evidence absent; full-length thymosin beta 4 evidence is not interchangeable
Reviewed 23 July 2026View research context

Specifications

Product details

Sequence / identity
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Molecular formula
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Molecular weight
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Storage and handling
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Batch documentationVerified record available

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Batch
TB5 004-016
Purity
99.3%
View batch record
Important research-use boundary

Health Canada lists the named compound or components among unauthorized injectable drugs identified in the Canadian market. A research-use label does not make an unauthorized product suitable or legal for personal use.

Explore the research

What has been studied?

Keep the context attached

Check what was studied, what researchers observed, and the limitation attached to each finding.

Question 01

Actin and cell migration

Laboratory research on thymosin beta 4 examines actin sequestration, cell movement and tissue-response pathways.

Evidence so far: Mechanistic evidence
Question 02

Topical ophthalmic research

A phase 2 dry-eye study tested full-length thymosin beta 4 solution and did not meet its two primary endpoints.

Evidence so far: Formulation-specific human trial
Question 03

TB-500 fragment

FDA reports no identified human exposure data for drug products containing the LKKTETQ fragment.

Evidence so far: Direct human evidence gap

Proposed mechanism

How researchers are investigating the mechanism.

Thymosin beta 4 binds actin and has been studied in cell migration and repair-related pathways. Even where the parent peptide shows biological activity, molecular identity, formulation and route determine whether a study is relevant to TB-500.

Study records

What was studied—and what was not.

See what researchers tested, what they observed and the limitation attached to each result.

Study 01Randomized, double-masked phase 2 study of topical full-length thymosin beta 4
What researchers saw
The two primary endpoints were not significantly different; selected secondary outcomes were reported.
Why that is not the whole story
A topical full-length peptide study is not evidence for an injectable fragment.
Read the original source
Study 02FDA review of thymosin beta 4 fragment (LKKTETQ/TB-500)
What researchers saw
FDA reported no identified human exposure data and insufficient information to characterize harm.
Why that is not the whole story
Evidence for the parent peptide cannot fill a fragment-specific safety gap.
Read the original source

Evidence gaps

What remains unknown?

  • Human pharmacology and safety of the TB-500 fragment are not established.
  • Product naming can obscure whether the tested material is full-length thymosin beta 4 or a fragment.
  • Route, formulation and purity data cannot substitute for molecularly matched clinical evidence.