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Peptide · Research use only

GHK-CU

From CA$55CAD

A naturally occurring copper-binding peptide explored in skin, collagen and wound-healing research.

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GHK-CUFrom CA$55

Product information

GHK-CU, clearly explained.

A naturally occurring copper-binding peptide explored in skin, collagen and wound-healing research.

Overview

GHK-Cu has been studied in human cells and in a small number of topical wound-care studies. Those findings are specific to the formulation and delivery method; they do not tell us what an injectable research material would do.

GHK-Cu is the copper complex of the naturally occurring tripeptide glycyl-L-histidyl-L-lysine. Published work spans fibroblast models, skin-delivery experiments and a limited set of topical wound studies.
Format
Vial
Available strengths
50mg · 100mg
Batch
GHK 006-031
Purity
99.5%
Research at a glanceMechanistic and limited topical human evidence; injectable evidence limited
Reviewed 23 July 2026View research context

Specifications

Product details

Sequence / identity
GHK-Cu
Molecular formula
Confirm in batch record
Molecular weight
403.93 g/mol
Storage and handling
Protect from direct light. Refer to the batch record for compound-specific handling conditions.
Batch documentationVerified record available

Review the analytical record connected to this exact batch.

Batch
GHK 006-031
Purity
99.5%
View batch record
Important research-use boundary

Health Canada lists the named compound or components among unauthorized injectable drugs identified in the Canadian market. A research-use label does not make an unauthorized product suitable or legal for personal use.

Explore the research

What has been studied?

Keep the context attached

Check what was studied, what researchers observed, and the limitation attached to each finding.

Question 01

Extracellular-matrix biology

Human fibroblast cultures have shown concentration-dependent changes in collagen and matrix-related markers.

Evidence so far: In-vitro human-cell evidence
Question 02

Topical wound research

An older controlled study evaluated a GHK-Cu gel as part of standardized care for diabetic neuropathic ulcers.

Evidence so far: Narrow topical human evidence
Question 03

Route matters

Topical or ex-vivo skin findings do not establish the safety or effects of an injectable product.

Evidence so far: Critical interpretation boundary

Proposed mechanism

How researchers are investigating the mechanism.

GHK binds copper(II), a metal involved in multiple enzymes. Laboratory studies have reported changes in collagen synthesis, glycosaminoglycans and extracellular-matrix remodelling, but the effect depends on concentration, formulation and experimental system.

Study records

What was studied—and what was not.

See what researchers tested, what they observed and the limitation attached to each result.

Study 01Cultured human fibroblasts exposed to GHK-Cu
What researchers saw
The study reported stimulation of collagen synthesis at low concentrations without a change in cell number.
Why that is not the whole story
A cell-culture response cannot establish a cosmetic, wound-healing or systemic clinical outcome.
Read the original source
Study 02Multicentre, randomized, evaluator-blinded topical gel study in diabetic neuropathic ulcers
What researchers saw
Investigators reported greater closure measures for plantar ulcers when the gel was added to standardized care.
Why that is not the whole story
The finding is formulation-, route-, wound- and care-protocol-specific and does not support injectable use.
Read the original source

Evidence gaps

What remains unknown?

  • The amount of evidence for systemic or injectable administration is very limited.
  • Formulation, copper stoichiometry, stability and route can materially change what is being studied.
  • Evidence for a topical clinical formulation cannot be transferred to a research vial.