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Peptide · Research use only

Retatrutide

From CA$150CAD

An experimental compound designed to act on three metabolic hormone receptors at the same time.

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RetatrutideFrom CA$150

Product information

Retatrutide, clearly explained.

An experimental compound designed to act on three metabolic hormone receptors at the same time.

Overview

Retatrutide has reached phase 3 clinical research for weight and blood-sugar outcomes, but it remains investigational and is not approved for public use. Trial findings apply to the sponsor’s controlled product—not a separately sourced material.

Retatrutide is a single investigational peptide designed to activate GIP, GLP-1 and glucagon receptors. It remains under clinical development and is not an approved public-use medicine as of this review.
Format
Vial
Available strengths
10mg · 20mg · 30mg
Batch
RETA 002-044
Purity
99.2%
Research at a glancePhase 2 and emerging phase 3 human evidence; still investigational
Reviewed 23 July 2026View research context

Specifications

Product details

Sequence / identity
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Molecular formula
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Molecular weight
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Storage and handling
Follow the batch-specific conditions included with the product documentation.
Batch documentationVerified record available

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Batch
RETA 002-044
Purity
99.2%
View batch record
Important research-use boundary

Retatrutide remains investigational. FDA states it has not been found safe and effective for any condition and cannot be used in compounding under U.S. federal law; Health Canada lists unauthorized injectable retatrutide among products consumers should not buy or use.

Explore the research

What has been studied?

Keep the context attached

Check what was studied, what researchers observed, and the limitation attached to each finding.

Question 01

Obesity and overweight

Phase 2 and phase 3 programmes study body-weight change and related outcomes under controlled escalation schedules.

Evidence so far: Human randomized trials
Question 02

Type 2 diabetes

A 2026 phase 3 trial reported HbA1c and body-weight outcomes over 40 weeks in adults inadequately controlled by diet and exercise.

Evidence so far: Published phase 3 evidence
Question 03

Safety and tolerability

Trials report gastrointestinal events and other dose-related observations; longer-term outcomes remain under study.

Evidence so far: Evolving clinical safety database

Proposed mechanism

How researchers are investigating the mechanism.

The molecule combines incretin-receptor signalling with glucagon-receptor activity. Clinical trials assess the net effect on glycaemia, appetite-related outcomes, body weight and safety rather than assuming each receptor contributes independently.

Study records

What was studied—and what was not.

See what researchers tested, what they observed and the limitation attached to each result.

Study 01Randomized, double-blind 48-week phase 2 trial in 338 adults with obesity
What researchers saw
The publication reported dose-dependent body-weight changes and gastrointestinal adverse events.
Why that is not the whole story
Trial results apply to Lilly's investigational material and protocol, not a separately sourced product.
Read the original source
Study 02Randomized, double-blind 40-week phase 3 trial in adults with type 2 diabetes
What researchers saw
The 2026 publication reported HbA1c and body-weight outcomes across retatrutide and placebo groups.
Why that is not the whole story
Published phase 3 data do not equal regulatory approval or establish safe public access.
Read the original source

Evidence gaps

What remains unknown?

  • Regulatory review is not complete, and no public-use retatrutide product has been approved.
  • Long-term cardiovascular, pancreatic, gallbladder and other safety questions require the complete development programme and regulatory review.
  • FDA states retatrutide cannot be used in compounding under U.S. federal law.